Search - Chemotherapy

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Description

Chemotherapy is the medical treatment which is given to cancer patients to destroy fast multiplying cells in the body. The drugs are called as chemotherapeutic agents/drugs. Targeted therapy is a form of treatment in which drugs act by targeting specific receptors on cancer cells. This form of therapy is less toxic, but it has side effects too. Broadly chemotherapy may be classified based on if given before surgery or after surgery or along with radiation therapy. 1. Combined modality chemotherapy 1. Combined modality chemotherapy Neo-adjuvant Chemotherapy – Chemotherapy which is given before surgery. It is given with an intent to reduce the size of the tumor to make it surgical resectable.Adjuvant Chemotherapy – Chemotherapy which is given after surgery. It is given with an intent to kill the cancer cells present in the blood circulation in the body.Concurrent Chemotherapy – Chemotherapy which is given when the patient receives radiation therapy. It is usually given once in a week, while the patient receives radiation therapy on a daily basis. Neo-adjuvant Chemotherapy Adjuvant Chemotherapy Concurrent Chemotherapy 2. Curative Chemotherapy 2. Curative Chemotherapy Chemotherapy when given with a curative intent is called as curative chemotherapy. It is usually given in the early stages of cancer. 3. Palliative chemotherapy 3. Palliative chemotherapy It is a chemotherapy given to the patient, when the disease is in stage IV, with an intent to improve the symptoms & improve the quality of life. The other kinds of chemotherapy are induction, consolidation and maintenance chemotherapy (in leukemia).

Symptoms

Chemotherapy may be used in the following cases: To cure cancer, as primary treatmentAfter other treatments, to kill any hidden or undetected cancer cellsTo shrink the tumor size so that other treatments become more effective To cure cancer, as primary treatment After other treatments, to kill any hidden or undetected cancer cells To shrink the tumor size so that other treatments become more effective Chemotherapy is also administered in bone marrow diseases and immune system disorders.

Pre Procedure

Depending on the chemotherapy will be administered, you might have to make certain preparations. In most cases, there is no special requirement to get chemotherapy. You may need to: Require chemoport, If chemotherapy will be administered intravenously.Undergo certain tests to ensure that the body is ready for chemotherapy.Check dental infection, in rare cases. Require chemoport, If chemotherapy will be administered intravenously. Undergo certain tests to ensure that the body is ready for chemotherapy. Check dental infection, in rare cases. You should eat and drink right during your chemotherapy sessions.

During Procedure

It is usually given in the form of Intravenous (blood administration), also given in the form of oral pills, intramuscular, spinal, peritoneal, directly into CSF.A single chemotherapeutic agent may be used or a combination of many drugs may be used at the same time or at different times. It can be given via intravenous line (through veins), or via Chemoport or PICC line (Peripherally Inserted Central Catheter). You may or may not be able to get admitted for chemotherapy. It is usually administered in day-care (where chemotherapy is administered for a few hours & then patient is discharged) under the supervision of paramedical staff. Chemotherapy may be administered over few seconds, or minutes or hours. It may be given over a period of few days also, depending on the treatment protocols, for which you may have to get admitted. Your doctor (medical oncologist) will decide which form of chemotherapy should be given to you based on age, cancer site, histological type, stage and other parameters. Some International organizations, such as, NCCN (National Comprehensive Cancer Network), ASCO (American Society of Clinical Oncology), ESMO (European Society for Medical Oncology) publish guidelines & protocols specifying dosage, schedule, method of administration of chemotherapy, duration of administration of chemotherapy etc. based on evidence based medicine. You will receive chemotherapy according to the chemotherapy protocols. You may receive chemotherapy daily, on alternate days, weekly, twice weekly, monthly or so on. It depends on the chemotherapy protocol (designed by the international organizations or personalized protocols).

Post Procedure

Chemotherapy leads to a period of few days of low immunity (low white blood cell counts), when you should be careful about onset of fever.Some patients feel much tried & weak after chemotherapy, the duration of which may vary.You should consult your doctor about working hours & also, you can discuss your work schedule with your employer.You can work during chemotherapy if you medically fit for the same. Chemotherapy leads to a period of few days of low immunity (low white blood cell counts), when you should be careful about onset of fever. Some patients feel much tried & weak after chemotherapy, the duration of which may vary. You should consult your doctor about working hours & also, you can discuss your work schedule with your employer. You can work during chemotherapy if you medically fit for the same.

Risk And Complications

Various types of chemotherapy agents have different side effects. The severity may vary from person to person. Few of the predictable side effects are: Fatigue – Weakness & tirednessPain – Generalized body pain, muscle pain, stomach pain, nerve damage painNausea/VomitingLoss of tasteLoss of appetiteChanges in the skin – Pigmentation, DrynessOral ulcersHair LossLoose stoolsConstipationNeutropenia – Low white blood cell count (low immunity)Anaemia – Low haemoglobinThrombocytopenia – Low platelet countPancytopenia – Low white blood cell count, haemoglobin & platelet countInfections – especially during the phase of low white blood cell countChanges in fertility These days, chemotherapy is not as scary as before. New drugs are available which are safe and more effective. Majority of side effects of chemotherapy are manageable with the help of supportive treatment. For example:Neutropenia – Low white blood cell count – is managed with the injections (filgrastim/peg filgrastim), which boost the white blood cell count.Anaemia – Low haemoglobin – is managed with the help of blood transfusion, erythropoiten stimulating agents & iron supplements, if required.Nausea/Vomiting – is managed with the help of intravenous medications before chemotherapy (called as pre medication), & with the help of oral medications after chemotherapy is over. Various combination of medications are used in different dosages depending upon the type of chemotherapy and severity of nausea/vomiting.Loose stools/constipation – can be managed with the help of supportive medications.Hair Loss – Currently it can’t be managed with the help of medications. However, hair loss is not permanent. Hair start growing again after the chemotherapy is over. Fatigue – Weakness & tiredness Pain – Generalized body pain, muscle pain, stomach pain, nerve damage pain Nausea/Vomiting Loss of taste Loss of appetite Changes in the skin – Pigmentation, Dryness Oral ulcers Hair Loss Loose stools Constipation Neutropenia – Low white blood cell count (low immunity) Anaemia – Low haemoglobin Thrombocytopenia – Low platelet count Pancytopenia – Low white blood cell count, haemoglobin & platelet count Infections – especially during the phase of low white blood cell count Changes in fertility These days, chemotherapy is not as scary as before. New drugs are available which are safe and more effective. Majority of side effects of chemotherapy are manageable with the help of supportive treatment. For example: Neutropenia – Low white blood cell count – is managed with the injections (filgrastim/peg filgrastim), which boost the white blood cell count. Anaemia – Low haemoglobin – is managed with the help of blood transfusion, erythropoiten stimulating agents & iron supplements, if required. Nausea/Vomiting – is managed with the help of intravenous medications before chemotherapy (called as pre medication), & with the help of oral medications after chemotherapy is over. Various combination of medications are used in different dosages depending upon the type of chemotherapy and severity of nausea/vomiting. Loose stools/constipation – can be managed with the help of supportive medications. Hair Loss – Currently it can’t be managed with the help of medications. However, hair loss is not permanent. Hair start growing again after the chemotherapy is over. Similarly, there are other side effects of chemotherapy, which may or may not be managed with the help of supportive treatment. Different types of chemotherapeutic agents have different types of side effects. Not everybody suffers from all side effects & severity of side effects may vary.
Hospital

Narayana Hrudayalaya, Jaipur

  Sec- Prathap Nagar-, 28, Kumbha Marg, Sector 6, Sanganer, Jaipur, Rajasthan 302033.

0141-7122222
0

Facilities

Blood Bank CT Scan MRI Scan PET Scan Dialysis

Narayana Multispeciality Hospital, Jaipur is a multispeciality tertiary care hospital offering high quality, affordable medical care. Narayana Multispeciality H....


Hospital

Soni Hospital

  38, Kanota Bagh, 302004.

0141-5163700
100

Departments

Cardiology ENT Neurology Ophthalmology Orthopaedics Dermatology Gynaecology Plastics Paediatrics ...

Soni group of hospitals started from its humble beginning as a 20-bedded Soni Nursing Home at J.L.N. Marg in 1986. Jaipur community valued its good services and....



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